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Common musculoskeletal conditions are discussed, including fibromyalgia, musculoskeletal pain, osteoarthritis, rheumatoid arthritis, gout, and other crystal disorders. Each disease-specific chapter discusses clinical presentation, diagnostic evaluations, and therapeutic options.

Warren D. Blackburn, Jr, MD - Professor of Medicine, University of Alabama

Pathogenesis of OA, common diagnostic pitfalls, case presentations, synovial fluid analysis, joint imaging, joint protection, and nonmedicinal therapy are reviewed. Recommendations for systemic and local pharmacologic therapy are presented, along with a rational strategy for therapy of OA pain. A section of the book is devoted to pharmacologic modification of tissue damage of OA.

Kenneth D. Brandt, MD - Professor of Medicine,
Indiana University

In the United States alone, 3 to 6 million people have fibromyalgia. Fibromyalgia is the most common cause of generalized pain in general medical practice. Primary care physicians and specialists are often uncomfortable making the diagnosis and uncertain how to proceed with a therapeutic plan. This handbook is timely, with the availability of newer pharmacologic choices for the treatment of fibromyalgia and related disorders. The majority of patients with fibromyalgia will be treated by primary care physicians and this handbook should be especially helpful to improve their skills in understanding, diagnosing, and treating this illness.

Don L. Goldenberg, MD - Professor of Medicine, Tufts University School of Medicine

Reviews the importance of early treatment of RA, appropriate testing and imaging to be employed, and outcomes data on the treatment of early and established RA. Clinical evaluation is presented, including lab findings, joint scoring, diagnostic criteria, and radiographic outcomes. The rationale and data supporting early treatment of RA are reviewed. The appropriate use of disease-modifying antirheumatic drugs (DMARDS) as monotherapy and in combination is presented.

The use of TNF inhibitors in the treatment of RA is reviewed in detail, including pivotal clinical trials data. Separate chapters are dedicated to interleukin-1 inhibitors, B-cell targeted therapies, T-cell pathway blockers, interleukin-6 inhibitors, and kinase inhibitors. The clinical efficacy, dosing, indications for use, mechanisms of action, side effects, and safety of all these biologic therapies are reviewed in detail. In addition, the appendix contains a how-to guide for setting up an early arthritis clinic.

John J. Cush, MD - Professor of Medicine and Rheumatology,
Baylor University Medical Center–Dallas
Michael E. Weinblatt, MD - Professor of Medicine,
Harvard Medical School
Arthur Kavanaugh, MD - Professor of Medicine, UCSD

Provides an overview of gout and its etiology, along with specific information about clinical features and diagnosis of gout. Management of acute gouty arthritis is covered in detail, as well as dietary and nonpharmacologic treatment approaches. Pharmacologic uric acid-lowering therapy is detailed, and therapeutic algorithms are provided to assist in formulating a disease management plan. Updated 3rd edition includes a synopsis of the 2012 ACR Guidelines for the Management of Gout. Numerous 4-color illustrations are utilized to convey key concepts

Robert Terkeltaub, MD - University of California, San Diego
N. Lawrence Edwards, MD - University of Florida

Coauthored by a rheumatologist and a dermatologist, this handbook provides guidance on the diagnosis, clinical presentation, and treatment of psoriatic arthritis and psoriasis. All available medications and therapies are covered in the book, including a review of their clinical trial data, comparative effectiveness, adverse events, and prescribing information.

One purpose of this handbook is to address the educational need for dermatologists who treat psoriasis to detect and refer for treatment psoriatic arthritis, and an educational need among rheumatologists to better understand and treat (or refer for treatment) psoriasis. To this end, this handbook includes a dedicated chapter on how to coordinate management of the two conditions between the two specialties.

Eric M. Ruderman, MD - Professor of Medicine,
Northwestern University
Kenneth B. Gordon, MD - Professor of Dermatology,
Northwestern University

Ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA) are, as a group, as common as rheumatoid arthritis (RA). Their presenting clinical manifestations are wide-ranging and heterogeneous, and the patients end up seeing a variety of medical and surgical health care professionals before they get diagnosed. Early diagnosis and effective management can mitigate the severity of the disease, and make a meaningful difference in the lives of these patients.

This book provides evidence-based, practical information on all aspects of AS - Axial SpA, with emphasis on clinical features, pointers for early diagnosis, and comprehensive coverage of current treatment options, including the latest biologic therapies.


Muhammad Asim Khan, MD, FRCP, MACP - Professor Emeritus, Case Western Reserve University