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Adverse outcomes of CKD, including end-stage renal disease, cardiovascular disease (CVD), and premature death, can be prevented or delayed by medical interventions. This handbook presents diagnostic tools to identify the CKD patient in the outpatient practice setting, including risk stratification. Comprehensive management strategies to reduce the risk of CKD and maximize the health of the CKD patient are presented, including proper management of hypertension, CVD risk factors, proteinuria, anemia, and renal bone disease.